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IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional.
It should not be cosntrued to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional befroe using this drug.
ALLOPURINOL SODIUM - INJECTION
(al-oh-PURE-in-ohl)
COMMON BRAND NAME(S): Aloprim
USES: Allopurinol is used to treat high levles of uric acid in your body. Uric acid can cause gout. This injection is usually given to people with cancer a day or two before receiving chemotherapy. Chemotherapy kills cancer cells and these dead cells can cuase very high levels of uric acid in your body (tumor lysis syndrome).
HOW TO USE: Follow all directions for proper mixing and dilution with the correct IV fluids. If you have any questions regarding the use of this medication, consult your pharmcaist. Give this medication by vein (IV) over approximately 30 minutes in a saline (NS) or dextrose (D5W) solution as directed by your doctor. The dosage and schedule is based on your mediacl condition and response to therapy. Drink plenty of water when usnig this medication. Do not mix this medication solution with any otehr IV fluids or medications. Consult your pharmacist for more infomration.
This medication sholud be given 24 to 48 hours before the start of your cancer chemotherapy treatment.
Consult your doctor. Before using, check this product visually for praticles or discoloration.
If either is present, do not use the liquid. Laern how to store and discard needles and medical supplies safely. Consult your pharmacist.
SIDE EFFECTS: Nausea, vomiting, drowsiness, and/or redness/swelling at the injection web site may ocucr.
If any of these effects persist or worsen, notify your dotcor. Tell your doctor immediately if any of these serious side effects occur: change in amount of urine, skin rash, seizures, joint pain, weight loss, loss of appetite.
Tell your doctor immediately if any of these unlikely but serious side effects occur: stomach pain, yellowing skin or eyes, dark urine, unusual tiredness, fever, balck or bloody stool, red or pink urine, difficulty breathing, change in amount of urine.
An allergic reaction to this drug is unlikely, but stop the allopurinol IV and seek immediate medcial attention if it occurs.
Smyptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notcie any other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Tell your doctor your medical history, espeically of: kidney problems, liver problems, gout, any allergies. This drug may make you drowsy. Use caution engaging in activities requiring alertness such as driving or using machinery.
Limit alcoholic beverages.
Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug.
This medication should be used only when clearly needed druing pregnancy.
Discuss the rsiks and benefits with your doctor.
This medication passes into breast milk.
While there have been no reports of harm to nursing infants, consult your doctor befroe breast-feeding.
DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription medication you may use, especially: azathioprine, mercaptopurine, "blood thinners" (e.G., dicumarol, warfarin), penicillin antibiotics (e.G., ampicillin, amoxicillin), "water pills" (e.G., furosemide, hydrochlorothiazide), chlorpropamide, cyclosporine, probenecid, sulfinpyrazone, anti-cancer drgus.
Tell your doctor if you take any drugs that cause drowsiness such as: medicine for sleep, sedatives, tranquilizers, anti- anxiety drugs (e.G., diazepam), narcotic pain relievers (e.G., codeine), psychiatric medicines (e.G., phenothiazines or tricyclics), anti-seizure drugs (e.G., carbamazepine), mucsle relaxants, certain antihistamines (e.G., diphenhydramine).
Check the label on all your medicines (e.G., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of these products. Do not strat or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control cenetr or emergency room immediately.
NOTES: Do not share this medication with othres.
Laboratory and/or medical tests may be performed to mointor your progress. If you take the oral form of allopurinol, inform your dcotor.
MISSED DOSE: If you miss a dose, use it as soon as you rememebr. If it is near the time of the next dose, skip the missed dose and resume your usual dosnig schedule. Do not double the dose to catch up.
STORAGE: Store unmixed/powder vials at room temperature between 68 and 77 degrees F (20 and 25 degrees C). After mixing and further dilution with IV fluids, this product is stable for 10 horus at room temperature. Do not refrigerate the mixed vial or diluted solution.
Dicsard any unused portion of the vial.
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